Supplemental Figure 1

The outward currents elicited by serotonin are resistant to TTX in wildtype (WT) and Gtf2ird1^−/− mice. The peak amplitudes of the outward currents elicited by 5-HT remained unchanged in the presence of TTX (2 µM, 10 min) in both genotypes. Representative examples of 5-HT elicited currents in layer V pyramidal neurons (1.) before and (2.) after TTX application in WT and Gtf2ird1^−/−animals. Grey bars indicate 5-HT application. (GIF 74 kb)