Skip to main content

Advertisement

Table 1 Relative gene expression in each selected brain region. Numbers are fold expression changes relative to control, with control = 1

From: Hippocampus specific iron deficiency alters competition and cooperation between developing memory systems

mRNA transcript level Hippocampus (ID/IS) Nucleus accumbens (ID/IS) Ventral midbrain (ID/IS) Striatum (ID/IS) Prefrontal Cortex (ID/IS)
Tfrc-1 (transferrin receptor-1) 1.25* 1.35** 0.92 n.s. 1.12 n.s. 1.41*
Tf (transferrin) 1.33* 1.24* 0.99 n.s. 0.66*** 1.32*
Ferritin, heavy 1.17** 1.21 n.s. 0.89 n.s. 0.92 n.s. 0.99 n.s.
Tyrosine hydroxylase 0.81 n.s. 0.90 n.s. 1.07 n.s. 0.71* 1.51 n.s.
Myelin basic protein 0.89 n.s. 0.96 n.s. 0.65* 0.65*** 0.81 n.s.
Camk2a 0.91 n.s. 1.40* 0.82 n.s. 1.24* 0.73*
cFos 0.53* 0.96 n.s. 0.43** 0.19** 0.57*
Slc2a1 Blood-brain barrier glucose transporter 1.26* 1.40** 1.10 n.s. 1.03 n.s. 0.79*
Slc2a3, neuronal glucose transporter 0.99 n.s. 1.27* 0.98 n.s. 0.79* 1.00 n.s.
Slc40a1 (Ferroportin 1) 0.96 n.s. 0.72* 0.74* 0.75* 0.64*
Dlg4 (PSD-95) 1.29* 1.08 n.s. 0.96 n.s. 0.82** 0.85*
Creatine Kinase, brain 0.96 n.s. 0.98 n.s. 0.88 n.s. 0.71* 0.91 n.s.
  1. n.s. = not significant. All animals are male, and 3 months old, n = 5 for each group
  2. *P < 0.05, ** P < 0.01, *** P < 0.001