Atypical development of the executive attention network in children with chromosome 22q11.2 deletion syndrome

Table 5 22q11.2DS only: surviving factors and interactions

Selected factors^a	Mixed model estimates of fixed effects on LnAdjRT
Selected factors^a	Estimate (β) (×10²)^b	Standard error (×10²)	Significance (p)^c	Description (e^β followed by specified condition)
Age	−0.684	0.158	<0.001	0.69% benefit per month of age
Age × flanker	−0.231	0.078	0.025	0.23% additional benefit per month of age on incongruent flankers
Flanker	51.4	9.9	<0.001	67% cost on incongruent flankers
Cue	17.1	1.9	<0.001	19% cost on invalid cues
	14.8	1.9	<0.001	16% cost on no cue
	17.2	1.9	<0.001	19% cost on neutral cue
Variance
Residual	2.6	1.6		2.6% of the total variation
Participants	4.6	1.0		4.7% of the total variation

^aDetermined by type III sum of squares (see “Methods” for criteria)
^bSome parameters were set to 0 because they are used as the reference parameter for modeling. They are diagnosis = typically developing, gender = female, flanker = single, and cue = valid. For interactions, if any condition tested contains a reference, that estimate is set to 0
^cFor clarity, parameter estimates are reported only if the factor it modifies significantly contributed to the model. For example, age × flanker survived entry criteria, but of the age × flanker interactions, only the age by incongruent condition significantly contributed to the model and is presented here. p Values are Bonferroni adjusted for eight comparisons

ISSN: 1866-1955