Self and Other Faces task shows visual response in middle cingulate cortex. (A) Self-Other Faces task paradigm. Twenty-five healthy adult participants were shown pictures of themselves (15 unique pictures, eyes forward and smiling) and pictures of another gender-matched volunteer (15 unique pictures, eyes forward and smiling). The pictures were shown for 4 s and in a randomized order. The inter-trial interval was jittered using 2 s, 4 s, or 6 s. (B) Time-series of BOLD response in middle cingulate cortex during Self-Other Faces task. (Inset: ROI mask derived from structured imagery task (see Figure 4)). Mean BOLD response (% signal change from baseline) along the vertical axis; time (s) along the horizontal axis. Pictures are displayed at time = 0 s for a duration of 4 s. Error bars: Standard error around the mean; asterisks: p < 0.05, (one-tailed t-test, n = 25 subjects: ‘self’-picture response > ‘other’-picture response).