Figure 1

Ventricular enlargement and cortical focal grey matter volumes in children with PWS and healthy controls. Top row: ventricular enlargement in children with PWS. (I) Healthy control; (II) child with DEL; and (III) child with mUPD. All three presented children were of the same age and gender. Lower three rows: cortical focal measures in children with PWS and healthy controls. Cortical surface is presented inflated with curvature overlay (in green and red shades). Second row: children with DEL compared to healthy controls; third row: children with mUPD compared to healthy controls; last row: children with mUPD compared to children with DEL. All the views are in sagittal plane. Columns (from left to right): left lateral, left medial, right medial, and right lateral. DEL, deletion; mUPD, maternal uniparental disomy; PWS, Prader–Willi syndrome.