The neural correlates of visuo-spatial working memory in children with autism spectrum disorder: effects of cognitive load

Table 6 Regions of significant differences between TD and ASD groups

Voxels	MNI Coordinates			Z value	P value	Hem.	Region
	x	y	z
810	0	−56	46	3.93	1.56 × 10⁻³	L	Precuneus
X	10	−66	40	3.81		R	Precuneus
796	34	34	40	3.65	1.76 × 10⁻³	R	Dorsolateral prefrontal cortex
X	−6	26	46	3.13		L	Dorsal medial premotor cortex

Results from between group comparisons of the linear trend analyses from D3 to D6. All regions reported are areas in which TD children showed greater positive linear relations between cortical activity and difficulty level (i.e. increasing BOLD signal with increasing difficulty) than children with ASD. There were no areas where children with ASD showed greater linear relations between cortical activity and difficulty level than TD children. MNI coordinates represent the peak Z value of the cluster; X peak local maximas within cluster.

ISSN: 1866-1955