Table 2 Acquired developmental milestones: expressive and receptive language
From: Developmental delay in Rett syndrome: data from the natural history study
Skill | Classic (N = 542, 5 without answers) | Atypical better (N = 50) | Atypical poorer (N = 46, 1 without answers) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Acquired | Lost | Retained | Acquired | Lost | Retained | Acquired | Lost | Retained | |
Receptive communication | |||||||||
Fix and follow | 94 (503) | 28 (143) | 86 (464) | 94 (47) | 8.5 (4)* | 94 (47) ● | 89 (40) | 7.6 (3)* | 85 (39) |
Quiet to voice | 85 (457) | 26 (118) | 77 (416) | 84 (42) | 7.1 (3)* | 84 (42) | 71 (32)* | 0 (0) | 71 (32) |
Inhibit to no | 66 (357) | 25 (88) | 56 (303) | 76 (38) | 7.9 (3) ● | 72 (36)* | 47 (21)* | 10 (2) | 42 (19) ● |
Follow command with gesture | 55 (295) | 36 (107) | 42 (225) | 74 (37)* | 16 (6)* | 68 (34) ◊ | 29 (13) ◊ | 7.7 (1)* | 27 (12) ● |
Follow command with no gesture | 45 (241) | 32 (76) | 36 (195) | 70 (35) ◊ | 20 (7) | 62 (31) ◊ | 24 (11)* | 9.1 (1) | 22 (10) ● |
Expressive communication | |||||||||
Social smile | 99 (535) | 16 (85) | 96 (518) | 100 (50) | 10 (5) | 100 (50) | 98 (44) | 14 (6) | 96 (43) |
Coo | 93 (499) | 36 (178) | 67 (360) | 98 (49) | 14 (7)* | 86 (43) ◊ | 78 (35)* | 31 (11) | 56 (25) |
Babble | 95 (511) | 51 (259) | 64 (346) | 98 (49) | 18 (9) ◊ | 90 (45) ◊ | 80 (36) ◊ | 33 (12) | 62 (28) |
Single words | 77 (412) | 86 (354) | 21 (113) | 94 (47)* | 55 (26) ◊ | 68 (34) ◊ | 36 (16) ◊ | 13 (2) ◊ | 36 (16) ● |
Phrases | 18 (98) | 76 (74) | 5.0 (28) | 54 (27) ◊ | 41 (11) ◊ | 42 (21) ◊ | 6.7 (3) | 0 (0) | 6.7 (3) |
Gestures | 53 (286) | 86 (246) | 10 (56) | 70 (35)* | 46 (16) ◊ | 44 (22) ◊ | 31 (14)* | 50 (7)* | 18 (8) |
Points for wants | 23 (121) | 65 (79) | 9.5 (51) | 58 (29) ◊ | 28 (8) ◊ | 44 (22) ◊ | 4.4 (2)* | 100 (2) | 0 (0) ◊ |