Table 1 Medical/health features examined in premutation carriers
From: Associated features in females with an FMR1 premutation
Medical/health features | Strength of evidence-those with FXTAS | Strength of evidence-asymptomatic of FXTAS | Strength of evidence - association with genetic markers |
|---|---|---|---|
Thyroid Disease | Probably related | Possibly related | Possible association with CGG repeat length |
Hypertension | Possibly related | Possibly related | Possible association with CGG repeat length |
Fibromyalgia symptoms | Probably related | Possibly related | Possible association with CGG repeat length |
Migraine | Possibly related | Possibly related | Not found to be associated with CGG repeat length |
Neuropathy | Definitely related | Probably related | Severity related to CGG repeat length after controlling for AR |
Vestibular difficulties | Probably related | Probably related | Relationship not yet examined |