Table 2 Reproductive features examined in female premutation carriers with and without FXPOI
From: Associated features in females with an FMR1 premutation
Reproductive features | Strength of evidence - those with FXPOI | Strength of evidence-those without FXPOI | Strength of evidence - association with genetic markers |
|---|---|---|---|
Ovarian insufficiency | Definitely related | Definitely related | Strong evidence of nonlinear associate with CGG |
Estrogen-related conditions | Definitely related | Possibly related | Possible association with CGG repeat length |
Fertility issues | Definitely related | Definitely related | Strong evidence of nonlinear associate with CGG |
Obstetric and perinatal difficulties | Possibly related | Possibly related | Relationship not yet examined |
Postpartum depression | Possibly related | Possibly related | Relationship not yet examined |