Table 4 PIF effect on HESC analyzing maps, processes, disease ranking, and strength of association

Development_angiotensin signaling via beta-arrestin

0.001218

Neurophysiological process_transmission of nerve impulse_

1.114E - 06

Nervous system development

1.736E - 16

Autistic disorder

4.026E - 14

Development_regulation of epithelial-to-mesenchymal transition (EMT)

0.001379

Muscle contraction

0.0005106

Positive regulation of biological process

7.282E - 16

Child development disorders, pervasive

4.887E - 14

G-protein signaling_RhoB regulation pathway

0.003256

Cytoskeleton_regulation of cytoskeleton rearrangement

0.0009131

Cell communication

5.021E - 15

Mood disorders

2.655E - 09

Cell adhesion_tight junctions

0.004814

Development_neurogenesis: axonal guidance

0.001197

Regulation of transport

9.227E - 15

Stress

2.787E - 09

Muscle contraction_GPCRs in the regulation of smooth muscle tone

0.005149

Reproduction_GnRH signaling pathway

0.008079

Anatomical structure development

1.207E - 14

Mental disorders diagnosed in childhood

6.579E - 09

Cytoskeleton remodeling_TGF, WNT, and cytoskeletal remodeling

0.005462

Cell adhesion_cell junctions

0.01565

Regulation of localization

1.48E - 14

Aortic diseases

6.6E - 09

Atherosclerosis_role of ZNF202 in regulation of expression of genes involved in atherosclerosis

0.007208

Signal transduction_cholecystokinin signaling

0.02107

Regulation of amine transport

1.744E - 14

Aortic aneurysm

6.801E - 09

Transcription_CREB pathway

0.009855

Signal transduction_TGF-beta, GDF, and activin signaling

0.02518

Transmission of nerve impulse

2.15E - 14

Craniomandibular disorders

1.025E - 08

Cell adhesion_role of CDK5 in cell adhesion

0.01212

Signal transduction_WNT signaling

0.02811

Positive regulation of cellular process

2.762E - 14

Temporomandibular joint disorders

1.025E - 08

Development_TGF-beta-dependent induction of EMT via MAPK

0.01239

Reproduction_gonadotropin regulation

0.02941

Regulation of multicellular organismal process

3.763E - 14

Mandibular diseases

5.041E - 08