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Table 2 Electromyographically recorded startle eyeblink responses at baseline (no pre-pulse presented) and following presentations of subtle acoustic pre-pulses at 120- and 480-ms lead intervals

From: Pre-pulse inhibition and antisaccade performance indicate impaired attention modulation of cognitive inhibition in 22q11.2 deletion syndrome (22q11DS)

 

22q11DS (n = 17)

HC group (n = 19)

  

%PPI or %PPF

 

%PPI or %PPF

Passive listening task

    

  Baseline startle

111.98 (±73.07) μV

 

133.2 (±117.3) μV

 

  120-ms pre-pulse

87.08 (±65.25) μV

22.8 (±5.6)

109.3 (±103.8) μV

17.1 (±8.3)

  480-ms pre-pulse

136.08 (±81.6) μV

-24.4 (±11.7)

131.2 (±100.8) μV

-3.1 (±8.5)

Active discrimination task

    

  Baseline startle

94.9 (±69.1) μV

 

104.9 (±72.6) μV

 

  120-ms pre-pulse

73.7 (±61.0) μV

15.5 (±11.9)

68.6 (±53.1) μV

34.1 (±5.4)

  480-ms pre-pulse

99.0 (±84.7) μV

-12.8 (±18.3)

114.2 (±86.2) μV

-23.3 (14.0)

  1. Resulting percent change as pre-pulse inhibition (%PPI) or pre-pulse facilitation (%PPF) relative to baseline startle response (standard error mean in parenthesis).