| | |
22q11DS
| |
Controls
| |
|---|
|
Brain region
|
BA
|
X
|
Y
|
Z
|
Size
|
p
value
|
X
|
Y
|
Z
|
Size
|
p
value
|
|---|
|
FEAR
| | | | | | | | | | | |
|
Middle occipital gyrus
| | | | | | | | | | | |
|
Right
|
18
|
29
|
-78
|
-7
|
8
| | | | | | |
|
Lingual gyrus
| | | | | | | | | | | |
|
Right
|
18
|
18
|
-78
|
-7
|
5
| | | | | | |
|
Precentral gyrus
| | | | | | | | | | | |
|
Left
|
4
| | | | | |
-36
|
-22
|
48
|
76
|
0.007657
|
|
Postcentral gyrus
| | | | | | | | | | | |
|
Left
|
2
| | | | | |
-47
|
-19
|
31
|
10
| |
|
Inferior parietal lobule
| | | | | | | | | | | |
|
Left
|
40
| | | | | |
-40
|
-30
|
42
|
16
| |
|
Cerebellum
| | | | | | | | | | | |
|
Left
| | | | | | |
-40
|
-63
|
-29
|
83
|
0.006032
|
|
Right
| |
29
|
-78
|
-13
|
62
|
0.00486
|
32
|
-63
|
-29
|
83
|
0.007889
|
|
DISGUST
| | | | | | | | | | | |
|
Inf-post temporal lobe
| | | | | | | | | | | |
|
Right
|
37
|
36
|
-56
|
-2
|
96
|
0.008705
| | | | | |
|
Middle occipital gyrus
| | | | | | | | | | | |
|
Right
|
18
|
32
|
-78
|
4
|
17
| | | | | | |
|
Inferior occipital gyrus
| | | | | | | | | | | |
|
Right
|
19
|
32
|
-78
|
9
|
7
| | | | | | |
|
Fusiform gyrus
| | | | | | | | | | | |
|
Right
|
37
|
36
|
-56
|
-7
|
37
| | | | | | |
|
Middle temporal gyrus
| | | | | | | | | | | |
|
Right
|
21
|
54
|
-37
|
-2
|
6
| | | | | | |
|
Lingual gyrus
| | | | | | | | | | | |
|
Right
|
18
| | | | | |
14
|
-85
|
-7
|
106
|
0.004004
|
|
Medial frontal gyrus
| | | | | | | | | | | |
|
Left
|
6
| | | | | |
-4
|
4
|
48
|
66
|
0.005116
|
|
Cingulate gyrus
| | | | | | | | | | | |
|
Left
|
24
| | | | | |
-4
|
4
|
42
|
15
| |
|
Cerebellum
| | | | | | | | | | | |
|
Right
| |
29
|
-63
|
-13
|
9
| |
25
|
-70
|
-13
|
9
| |
- Brain regions showing significant trends of activation to increasing intensity of emotion (neutral, mild, intense) for fearful and disgusted expressions. Both groups showed positive trend (i.e. increasing activation with the increasing emotional intensity) for ‘fear’. For ‘disgust’, the 22q11DS group showed positive trend whereas the controls showed negative trends (i.e. decreasing activation with increasing emotional intensity—shown in italics). Statistical thresholds adjusted so as to get less than one false positive cluster per map.
