Journal of Neurodevelopmental Disorders

Table 2 The effect of emotional intensity

From: An fMRI study of facial emotion processing in children and adolescents with 22q11.2 deletion syndrome

		22q11DS					Controls
Brain region	BA	X	Y	Z	Size	p value	X	Y	Z	Size	p value
FEAR
Middle occipital gyrus
Right	18	29	-78	-7	8
Lingual gyrus
Right	18	18	-78	-7	5
Precentral gyrus
Left	4						-36	-22	48	76	0.007657
Postcentral gyrus
Left	2						-47	-19	31	10
Inferior parietal lobule
Left	40						-40	-30	42	16
Cerebellum
Left							-40	-63	-29	83	0.006032
Right		29	-78	-13	62	0.00486	32	-63	-29	83	0.007889
DISGUST
Inf-post temporal lobe
Right	37	36	-56	-2	96	0.008705
Middle occipital gyrus
Right	18	32	-78	4	17
Inferior occipital gyrus
Right	19	32	-78	9	7
Fusiform gyrus
Right	37	36	-56	-7	37
Middle temporal gyrus
Right	21	54	-37	-2	6
Lingual gyrus
Right	18						14	-85	-7	106	0.004004
Medial frontal gyrus
Left	6						-4	4	48	66	0.005116
Cingulate gyrus
Left	24						-4	4	42	15
Cerebellum
Right		29	-63	-13	9		25	-70	-13	9

Brain regions showing significant trends of activation to increasing intensity of emotion (neutral, mild, intense) for fearful and disgusted expressions. Both groups showed positive trend (i.e. increasing activation with the increasing emotional intensity) for ‘fear’. For ‘disgust’, the 22q11DS group showed positive trend whereas the controls showed negative trends (i.e. decreasing activation with increasing emotional intensity—shown in italics). Statistical thresholds adjusted so as to get less than one false positive cluster per map.

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ISSN: 1866-1955

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