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Table 2 The effect of emotional intensity

From: An fMRI study of facial emotion processing in children and adolescents with 22q11.2 deletion syndrome

   22q11DS   Controls  
Brain region BA X Y Z Size p value X Y Z Size p value
FEAR            
Middle occipital gyrus            
Right 18 29 -78 -7 8       
Lingual gyrus            
Right 18 18 -78 -7 5       
Precentral gyrus            
Left 4       -36 -22 48 76 0.007657
Postcentral gyrus            
Left 2       -47 -19 31 10  
Inferior parietal lobule            
Left 40       -40 -30 42 16  
Cerebellum            
Left        -40 -63 -29 83 0.006032
Right   29 -78 -13 62 0.00486 32 -63 -29 83 0.007889
DISGUST            
Inf-post temporal lobe            
Right 37 36 -56 -2 96 0.008705      
Middle occipital gyrus            
Right 18 32 -78 4 17       
Inferior occipital gyrus            
Right 19 32 -78 9 7       
Fusiform gyrus            
Right 37 36 -56 -7 37       
Middle temporal gyrus            
Right 21 54 -37 -2 6       
Lingual gyrus            
Right 18       14 -85 -7 106 0.004004
Medial frontal gyrus            
Left 6       -4 4 48 66 0.005116
Cingulate gyrus            
Left 24       -4 4 42 15  
Cerebellum            
Right   29 -63 -13 9   25 -70 -13 9  
  1. Brain regions showing significant trends of activation to increasing intensity of emotion (neutral, mild, intense) for fearful and disgusted expressions. Both groups showed positive trend (i.e. increasing activation with the increasing emotional intensity) for ‘fear’. For ‘disgust’, the 22q11DS group showed positive trend whereas the controls showed negative trends (i.e. decreasing activation with increasing emotional intensity—shown in italics). Statistical thresholds adjusted so as to get less than one false positive cluster per map.