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Table 3 The main effect of group and group × intensity interaction

From: An fMRI study of facial emotion processing in children and adolescents with 22q11.2 deletion syndrome

   Fear   Disgust  
Brain region BA X Y Z Size p value X Y Z Size p value
Controls > 22q11DS            
Fusiform gyrus            
Left 19 -36 -74 -13 27   -40 -70 -18 49  
Right 19       29 -81 -13 119 0.003945
Inferior occipital gyrus            
Left 19 -36 -78 -7 5       
Insula            
Left 13       -29 -30 26 10  
Superior frontal gyrus            
Right 6 4 11 48 164 0.003543      
Postcentral gyrus            
Left 3 -32 -30 48 37   -29 -30 48 180 0.001517
Precentral gyrus            
Left 4 -36 -19 48 136 0.000273 -36 -19 53 21  
Transverse temporal gyrus            
Left 41       -47 -22 9 5  
Cingulate gyrus            
Right 32 0 11 37 33       
Cerebellum            
Left   -36 -79 -18 186 0.000273 -40 -44 -24 173 0.000305
Right        25 -74 -24 40  
GROUP × INTENSITY            
Fusiform gyrus            
Left 19       -32 -74 -18 22  
Precentral gyrus            
Left 4 -32 -22 53 50 0.005263 -29 -22 53 92 0.00246
Medial frontal gyrus            
Right 6       0 -11 53 7  
Superior frontal gyrus            
Right 6       0 4 48 23  
Cingulate gyrus            
Right 24       0 4 42 63 0.006812
Postcentral gyrus            
Left 3 -32 -33 48 21   -32 -22 42 27  
Inferior parietal lobule            
Left 40       -47 -30 31 5  
Cerebellum            
Left        -40 -70 -24 99 0.002271
  1. Brain regions showing main effects of group and group × intensity level interactions for each emotion experiment. Talairach coordinates in italic print indicate the most activated voxel within a cluster. Other Talairach coordinates represent other active areas in clusters (derived from decomposition of each cluster into contiguous slices, 5.72-mm diameter in the z dimension). Statistical thresholds adjusted so as to get less than one false positive cluster per map.