Cerebral volumetric abnormalities in Neurofibromatosis type 1: associations with parent ratings of social and attention problems, executive dysfunction, and autistic mannerisms

Table 1 Mean scores (SD) on social, cognitive, and behavioral outcome measures (NF1 = 15; HC = 12), corrected for age (MANOVA using group and sex as factors and age as covariate)

	NF1	HC	F	p	η_p ²
SSRS total^a	44.7 (13.7)	67.6 (7.6)	10.786	0.004	0.339
CBCL social problems	8.6 (4.7)	1.5 (1.5)	12.095	0.002	0.365
CBCL attention problems	9.5 (4.3)	2.4 (3.7)	5.387	0.030	0.204
SRS autistic mannerisms	24.9 (6.0)	13.6 (1.9)	11.486	0.003	0.354
BRIEF-GEC	149.5 (33.7)	97.4 (20.1)	8.582	0.008	0.290
DEX total	32.5 (16.8)	12.7 (14.4)	2.451	0.132	0.105

NF1 neurofibromatosis type 1, HC healthy control, SSRS social skills rating system, CBCL child behavior checklist, SRS social responsiveness scale, BRIEF-GEC behavior rating inventory of executive function-global executive composite, DEX dysexecutive questionnaire
^aHigher scores indicate fewer problems

ISSN: 1866-1955