Fig. 7

Absence of DTNBP1 genotype differences in scaffolding proteins in PSD enrichments of the frontal cortex and hippocampus. a, e Main effects of DTNBP1 genotype on abundance of PSD-95 and SAP102 in PSD enrichments of the frontal cortex. b Developmental trajectories of PSD-95 in wild-type (+/+), heterozygous DTNBP1 mutant (+/−), and homozygous DTNBP1 null mutant (−/−) mice in the PSD of the frontal cortex. f Developmental trajectories of SAP102 in wild-type (+/+) and homozygous DTNBP1 null mutant (−/−) mice in the PSD of the frontal cortex. c, g Main effects of DTNBP1 genotype [wild-type (+/+) and homozygous DTNBP1 null mutant (−/−)] on abundance of PSD-95 and SAP102 in PSD enrichments of the hippocampus. d, h Developmental trajectories of PSD-95 and SAP102 in wild-type (+/+) and homozygous DTNBP1 null mutant (−/−) mice in the PSD of the hippocampus. PSD postsynaptic density, cSM crude synaptic membrane, FCx frontal cortex, N.S. not significant. Error bars represent SEM