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Table 2 Characteristics of negative and positive SIPS scores and social competences in 22q11.2DS and control peers

From: Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome

 

22q11.2DS

Control

Main effect of group

Test

Median or mean (SD)

Min-max

Median or Mean (SD)

Min-max

z a

W or F(df,df)

p

Psychopathology

 Positive symptomsb

3

0–12

0

0–9

 

625

7.5 × 10−4

 Negative symptomsb

6

1–17

0.38

0–2

 

831

5.8 × 10−11

 Disorganized symptomsb

1

0–9

0

0–2

 

723.5

1.2 × 10−07

 General symptomsb

0

0–7

0

0–4

 

469.5

0.32

Social functioning

 ABASsocial c

99.89 (18.6)

256–606

126.1 (9.26)

110–138

−2.77

61.02 (1,50)

2.9 × 10−10

Social skills

 SRStotal b

64

15–122

15.17

3–44

5.00

678

6.2 × 10−9

Social cognition

 TASITtotal b

38

16–56

52.83

37–58

−3.83

44.5

8.0 × 10−9

 ERTtotal c

40.83 (12.09)

16.67–64.44

64.52 (7.75)

47.67–77.78

−2.96

88.07 (1,53)

7.39 × 10−13

  1. Measures of psychopathology were obtained from the structured interview for prodromal syndromes (SIPS), The raw score obtained from the social domain of the Adaptive Behavior Assessment System (ABAS-II) was used as a measure of social function, social skills were the total score obtained from the Social Responsiveness Scale (SRS), social cognitive abilities were evaluated using total correct answers from The Awareness of Social Inference Test (TASIT) and the CANTAB Emotional Recognition Task (ERT)
  2. aMean z-scores for 22q11.2 group as calculated from mean control = 0 and SD = 1
  3. bGroup median reported; group differences determined from Wilcoxon rank-sum test
  4. cGroup mean reported, main effect of group accessed from two-way ANCOVA [between-group factor (22q11.2DS, controls); between subject’s factor: sex; covariate: age]
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Journal of Neurodevelopmental Disorders

ISSN: 1866-1955

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