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Table 1 Demographic and clinical data of the participants

From: Altered functional resting-state hypothalamic connectivity and abnormal pituitary morphology in children with Prader-Willi syndrome

 

PWS

Control

p value

Correlations with pituitary gland (in PWS only)

 

DEL

mUPD

 

rho

p value

Sample size (n)

14

13

28

   

Age (years)

13.7 (3.5)

12.5 (5.1)

13.0 (3.1)

.93

  

Age range (years)

8.1–21.4

6.0–23.3

7.1–18.0

   

Male (n)

6

3

11

   

Female (n)

8

10

17

   

IGF-I SDS

−2.0 (1.5)

−3.2 (1.9)

 

.04

.31

.14

TSH (mU/l)

2.2 (1.1)

2.4 (1.0)

 

.62

.51

.016

Free T4 (pmol/l)

16.6 (2.5)

16.2 (2.3)

 

.43

−.22

.32

T3 (nmol/l)

2.6 (.7)

3.2 (1.9)

 

.25

.11

.64

Reverse T3 (nmol/l)

.37 (0.6)

.38 (1.0)

 

.97

−.49

.03

ACTH (pmol/l)

30.2 (20.1)

30.3 (17.6)

 

1.0

−.36

.23

  1. Data expressed as mean (SD) or number. No significant differences were found in either age or gender distribution between the groups
  2. DEL deletion, mUPD maternal uniparental disomy, PWS Prader-Willi syndrome, SD standard deviation