The feasibility of using actigraphy to characterize sleep in Rett syndrome

Table 1 Participant characteristics

ID	Age	Diagnosis	Mutation	Seizure status	Gross motor function	Feeding	Medications⁺
ID	Age	Diagnosis	Mutation	Seizure status	Gross motor function	Feeding	Sleep	Seizure	Pain	Spasticity
1	1 year, 8 months	Atypical	p.P152R	None	Walks with assistance	Eats finger foods	N	Y	Y	N
2	4 years, 3 months	Classic	p.P362fs	None	Walks with assistance	Fed by mouth	N	N	N	N
3	6 years, 7 months	Classic	p.E137_L386del	Suspected	Walks with assistance	Fed by mouth	N	Y	N	N
4	8 years, 2 months	Classic	p.R168X	None	Walks with assistance	Fed by mouth	N	N	Y	Y
5	8 years, 3 months	Classic	p.R168X	Controlled	Cannot sit unsupported	Fed by mouth	N	Y	N	N
6	8 years, 3 months	Classic	p.P152R	Uncontrolled	Cannot sit unsupported	Fed by mouth, has g tube	N	Y	N	N
7	8 years, 10 months	Classic	p.R255X	Controlled	Cannot sit unsupported	Has g tube	N	N	Y	N
8	9 years, 4 months	MECP2-related disorder	p.R106W	Controlled	Walks independently	Eats with utensils with some spilling	N	N	N	N
9	10 years, 4 months	Classic	p.A131fs	Uncontrolled	Walks with assistance	Fed by mouth	N	Y	N	N
10	11 years, 9 months	Classic	Exon 4 deletion	Uncontrolled	Cannot sit unsupported	Eats finger food, has g tube	Y	Y	N	Y
11	12 years, 7 months	Classic	Deletion between exon 3 and 4	Uncontrolled	Cannot sit unsupported	Fed by mouth	N	Y	N	N
12	15 years, 4 months	Classic	p.P272fs	Controlled	Cannot sit unsupported	Fed by mouth, has g tube	N	Y	N	N
13	17 years, 1 month	Classic	p.K144X	Uncontrolled	Walks with assistance	Eats finger food	Y	Y	N	N

⁺Several participants were also on other medications for health conditions, such as acid reflux and constipation

ISSN: 1866-1955