The effects of intranasal oxytocin on reward circuitry responses in children with autism spectrum disorder

Table 2 Effects of oxytocin on functional activation

Phase	Reward condition	Region	Hem	k	BA	x	y	z	Z max
OT > PLC
Anticipation	Nonsocial	Frontal pole	R	316	10	41	95	38	3.99
		Anterior cingulate cortex	L	182	32	46	83	46	3.97
		Superior frontal cortex	L	83	–	49	74	65	3.31
		Orbital frontal cortex	R	76	–	23	79	30	3.26
		Orbital frontal cortex	L	52	–	58	72	27	3.16
		Nucleus accumbens	R	56	–	43	72	30	3.42
	Nonsocial > social	Anterior cingulate cortex	L	441	–	46	84	46	3.91
		Frontal pole	L	69	–	54	91	29	3.12
		Frontal pole	R	40	–	38	87	56	3.17
		Insular cortex	R	65	47	25	72	31	3.24
		Caudate nucleus	R	64	–	42	67	36	3.11
		Orbital frontal cortex	R	47	–	29	76	29	3.34
		Nucleus accumbens	R	21	–	42	71	30	3.09
Outcome	Nonsocial	Frontal pole	L	42		55	91	52	3.28
Outcome	Nonsocial	Orbital frontal cortex	R	39	–	21	75	30	3.35
OT < PLC
Outcome	Social	Frontal pole	R	50	–	24	91	37	3.29

Hem hemisphere, k cluster size in voxels, BA Brodmann area; Z max maximum z-value

ISSN: 1866-1955