Neural correlates of socio-emotional perception in 22q11.2 deletion syndrome

Table 4 Brain regions showing significant increase in emotional experience contrasts within and between groups

k	t	MNI (x,y,z)			Hemisphere	Region	BA
Healthy controls
Positive > Scrambled
2639	5.08	−8	−77	17	L	Cuneus	18
	5.05	−14	−77	8	L	Cuneus	17
	4.79	−12	−60	0	L	Lingual gyrus	18
1472	5.10	−18	−91	26	L	Cuneus	18
	5.09	−6	−95	19	L	Cuneus	18
894	7.16	21	−66	14	R	Posterior cingulate	31
	4.35	11	−62	12	R	Posterior cingulate	30
Negative > Scrambled
1008	4.93	15	−90	−7	R	Lingual gyrus	17
	3.97	14	−98	1	R	Cuneus	17
877	5.59	−16	−70	6	L	Cuneus	30
	4.24	−10	−65	4	L	Cuneus	30
	4.15	−21	−61	3	L	Posterior cingulate	30
Positive > Negative No cluster FEW < 0.05
22q11DS patients
Positive > Scrambled
1505	5.97	22	−54	55	R	Precuneus	7
	5.82	23	−60	50	R	Precuneus	7
	5.59	29	−62	60	R	Superior parietal lobule	7
	5.47	33	−56	63	R	Inferior Parietal Lobule	40
	5.10	26	−59	47	R	Superior parietal lobule	7
	4.95	23	−63	55	R	Precuneus	7
	4.31	26	−65	57	R	Superior parietal lobule	7
1066	6.38	−25	−41	70	L	Postcentral	2
	5.84	−34	−46	65	L	Postcentral	5
	5.82	−28	−41	63	L	Postcentral	5
					L	Lingual gyrus	18
					L	Lingual gyrus	18
830	5.54	−13	−79	−12	L	Lingual gyrus	18
	5.45	−7	−87	−17	L	Lingual gyrus	18
	4.15	−7	−87	−22	L	Lingual gyrus	18
	4.13	−7	−82	−14	L	Lingual gyrus	18
	3.82	−3	−88	−11	L	Lingual gyrus	18
486	5.47	−30	−58	57	L	Superior parietal lobule	7
	4.80	−24	−60	56	L	Precuneus	7
	4.62	−22	−67	58	L	Superior parietal lobule	7
	4.55	−33	−51	58	L	Superior parietal lobule	7
	4.24	−25	−64	61	L	Superior parietal lobule	7
	3.94	−17	−67	55	L	Precuneus	7
Negative > Scrambled No cluster FEW < 0.05
Positive > Negative No cluster FEW < 0.05
Group comparison
No cluster pFWEc < 0.05

Abbreviations: k cluster size, t t scores, MNI Montreal Neurological Institute, BA Brodman Area

ISSN: 1866-1955