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Table 2 Primary and secondary outcomes analyses (by treatment condition)a

From: Cognitive training for children and adolescents with fragile X syndrome: a randomized controlled trial of Cogmed

Variables

Non-adaptive control

Adaptive

p value

Baseline

Post-training

Baseline

Post-training

N

Mean

SD

N

Mean

SD

N

Mean

SD

N

Mean

SD

(A) Primary measures

 Leiter-Revised Spatial Memory

50

21.44

10.00

49

22.94

9.87

50

20.44

14.09

49

24.27

13.51

 

 Stanford Binet-5 Block Span

50

10.66

4.65

49

11.65

4.86

50

10.20

5.40

50

11.92

5.75

 

Visual Working Memory Composite (mean)

50

16.05

6.62

49

17.30

6.71

50

15.32

9.15

49

18.19

8.98

0.533

(B) Secondary measures

 Digit Span (auditory working memory)

49

8.02

4.02

48

8.54

3.82

49

7.51

4.69

49

8.53

5.12

0.888

BRIEF

 Parent—Working Memory

48

21.48

3.95

47

20.53

4.23

49

22.12

3.84

49

21.49

4.17

0.082

 Teacher—Working Memory

28

21.57

5.65

23

20.83

5.59

31

23.13

5.26

30

21.70

5.84

0.313

 Parent—Global Executive Composite

46

151.61

21.82

46

144.41

24.83

45

151.38

27.63

47

148.13

25.83

0.022

 Teacher—Global Executive Composite

27

143.30

32.06

22

142.36

34.04

29

143.79

32.28

30

137.83

33.75

0.182

Conners

 Parent—Inattention

47

17.98

5.88

46

16.67

6.72

49

18.80

6.32

49

17.53

6.95

0.527

 Teacher—Inattention

28

18.32

9.11

25

16.20

8.03

31

18.07

8.30

30

15.80

8.52

0.499

 Parent—Hyperactivity/Impulsivity

47

18.23

10.88

46

16.94

12.02

49

18.55

11.71

49

18.45

12.54

0.319

 Teacher—Hyperactivity/Impulsivity

28

25.50

14.76

11

29.73

16.90

31

22.90

16.46

14

22.64

17.47

0.820

KiTAP

 Distractibility Errors

43

16.84

11.02

40

14.83

11.58

40

15.35

10.27

41

13.29

11.38

0.920

 Alertness SD of RT

48

240.18

266.98

45

230.40

206.09

45

344.76

294.35

47

309.77

286.70

0.189

 Flexibility False Alarms

42

8.05

4.27

38

7.13

3.81

37

9.24

3.87

38

7.53

4.50

0.985

 Go NoGo False Alarms

47

4.34

4.84

44

4.93

5.39

41

4.00

4.96

46

5.35

5.08

0.153

  1. BRIEF Behavior Rating of Executive Function, SD standard deviation, RT reaction time, KiTAP Kiddie Test of Attentional Performance, GEC Global Executive Composite
  2. aResults adjusted for active training time