Behavioural and psychological characteristics in Pitt-Hopkins syndrome: a comparison with Angelman and Cornelia de Lange syndromes

Table 5 Median and interquartile ranges of ASD-related behaviours and percentage meeting criteria for ASD from the SCQ for participant groups: PTHS, AS and CdLS

		PTHS	AS	CdLS	Kruskal-Wallis tests/chi-squared test			Post hoc comparison: Mann-Whitney U test/chi-squared test
		PTHS	AS	CdLS	h/χ²	df	p value	Comparison	U/χ²	df	Z	p value	Effect size r/relative risk (95% CI)
SCQ—total	N	22	22	18
	Median	24	18	25	18.41	2	< .001	PTHS > AS	73.50	1	3.965	< .001	0.59 (large)
	IQR	3.75	7	7.57	18.41	2	< .001	PTHS > AS	73.50	1	3.965	< .001	0.59 (large)
SCQ—communication	N	22	22	18
	Median	8	6	6.93	25.70	2	< .001	PTHS > AS	55.00	1	4.555	< .001	0.69 (large)
	IQR	0.25	3	1.25	25.70	2	< .001	PTHS > AS	55.00	1	4.555	< .001	0.69 (large)
SCQ—restricted, repetitive and stereotyped behaviours	N	22	22	22
	Median	4	4	5	3.56	2	.169	N/A
	IQR	3	2.25	2.63	3.56	2	.169	N/A
SCQ—reciprocal social interaction	N	22	22	18
	Median	10.5	7	12	11.15	2	.004	PTHS > AS	132.00	1	2.598	.009	.39 (medium)
	IQR	4.25	5.25	5.25	11.15	2	.004	PTHS > AS	132.00	1	2.598	.009	.39 (medium)
Met ASD cut-off	N	22	22	18
Met ASD cut-off	N (%)	21 (95.5)	15 (68.2)	16 (88.9)	5.85	2	.049^a	PTHS > AS	5.50	1	–	.023	1.40 (1.04 to 1.89)^b

ISSN: 1866-1955