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Table 6 Median and interquartile range for PTHS and comparison syndrome groups: AS and CdLS, derived from [31] and one-sample Wilcoxon test

From: Behavioural and psychological characteristics in Pitt-Hopkins syndrome: a comparison with Angelman and Cornelia de Lange syndromes

Median scores PTHS (n = 24) AS (n = 66) [31] CdLS (n = 98) [31] One-sample Wilcoxon test
Comparison group [31] Z p value PTHS significance Effect size r
SQID familiar—total Median (IQR) 42.5 (15.25) 53 (48–55) 41.5 (35–48) AS 3.95 < .001 PTHS < AS .57 (large)
CdLS   .360   
SQID familiar—receive interaction Median (IQR) 11.5 (3) 13 (12–14) 10 (8.75–12) AS 3.21 .001 PTHS < AS .46 (medium)
CdLS 2.98 .003 PTHS > CdLS .43 (medium)
SQID familiar—interaction Median (IQR) 12 (4) 13.5 (12–14) 11 (10–13) AS 2.90 .004 PTHS < AS .42 (medium)
CdLS   .072   
SQID familiar—approach or initiate interaction Median (IQR) 8 (5) 13 (10–14) 10 (7–12) AS 4.21 < .001 PTHS < AS .61 (large)
CdLS 2.47 .014 PTHS < CdLS .36 (medium)
SQID familiar—performance Median (IQR) 12 (3) 14 (12–14) 11 (9–13) AS 3.83 < .001 PTHS < AS .55 (large)
CdLS   .528   
SQID unfamiliar—total Median (IQR) 35.5 (12.75) 41 (31–48) 26 (13.5–35) AS 2.88 .004 PTHS < AS .42 (medium)
CdLS 2.92 .004 PTHS > CdLS .42 (medium)
SQID unfamiliar—receive interaction Median (IQR) 9 (3) 10 (8–12) 6.5 (3–8) AS   .108   
CdLS 3.30 .001 PTHS > CdLS .48 (medium)
SQID unfamiliar—interaction Median (IQR) 9.5 (3) 11 (9–12) 7 (3–9) AS 3.03 .002 PTHS < AS .44 (medium)
CdLS 2.95 .003 PTHS > CdLS .43 (medium)
SQID unfamiliar—approach or initiate interaction Median (IQR) 6 (4.75) 10 (6.75–12) 5 (4–7.5) AS 3.72 < .001 PTHS < AS .54 (large)
CdLS 2.33 .020 PTHS > CdLS .34 (medium)
SQID unfamiliar—performance Median (IQR) 10 (3) 10 (7–13) 7 (2.75–9) AS   .203   
CdLS 2.16 .031 PTHS > CdLS .31 (medium)