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Table 1 Descriptive data of the sample by diagnostic outcome group

From: Early white matter development is abnormal in tuberous sclerosis complex patients who develop autism spectrum disorder

 

TSC-ASD

TSC+ASD

t

p

Subjects (n, %)

62, 57%

46, 43%

  

Sex (% male)

55%

52%

  

MSEL developmental quotient at 24 months (\( \overline{x} \) ± σ)

90.4 ± 19.8

61.5 ± 19.7

7.6

1.7 × 10− 11

Epilepsy Severity Score at 24 months (\( \overline{x} \) ± σ)

2.1 ± 1.6

3.6 ± 1.8

− 4.8

6.1 × 10− 6

ADOS-2 calibrated severity score (\( \overline{x} \) ± σ)

1.7 ± 0.8

6.4 ± 2.0

− 15.5

< 2.2 − 10−16

  1. MSEL Mullen Scales of early learning, ADOS autism diagnostic observation schedule