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Table 2 Descriptive data of the MRI sample by diagnostic outcome group

From: Early white matter development is abnormal in tuberous sclerosis complex patients who develop autism spectrum disorder

 

TSC-ASD

TSC+ASD

Scans (subjects) with ADOS

163 (66)

125 (49)

 Excluded: 36-month scans (n)

44

32

 Excluded: Post-surgical scans (n)

5

13

 Excluded: DWI artifact scans (n)

4

2

Total scans (subjects) in sample

109 (62)

78 (46)

Sedated scans (n, %)

109, 100%

77, 99%

Baseline MRI (n, %)

16, 15%

15, 19%

12 months MRI (n, %)

47, 43%

31, 40%

24 months MRI (n, %)

46, 42%

32, 41%

Age at baseline MRI (\( \overline{x} \) ± σ)

0.4 ± 0.2

0.6 ± 0.2

Age at 12 months MRI (\( \overline{x} \) ± σ)

1.1 ± 0.1

1.1 ± 0.2

Age at 24 months MRI (\( \overline{x} \) ± σ)

2.0 ± 0.2

2.0 ± 0.2

Subjects with 1 scan (n, %)

25, 40%

20, 44%

Subjects with 2 scans (n, %)

26, 42%

20, 43%

Subjects with 3 scans (n, %)

11, 18%

6, 13%