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Fig. 1 | Journal of Neurodevelopmental Disorders

Fig. 1

From: Developmental exposure to diesel exhaust upregulates transcription factor expression, decreases hippocampal neurogenesis, and alters cortical lamina organization: relevance to neurodevelopmental disorders

Fig. 1

mRNA levels of neurogenic transcription factors at PND3. mRNA levels of transcription factors Pax6 (a), Tbr2 (b), Tbr1 (c), Sp1 (d), and Creb1 (e) were measured in cortex samples from PND3 pups exposed to either DE or FA from E0 to PND3. mRNA levels were normalized to the house-keeping gene GAPDH. Results represent the mean (± SE) of 5 mice from different litters for each experimental group. For all five transcription factors measured, mRNA levels were significantly increased in DE exposed males when compared to FA males (*p < 0.05; **p < 0.01; ***p < 0.001; two-way ANOVA with Bonferroni post-test)

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Journal of Neurodevelopmental Disorders

ISSN: 1866-1955

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