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Table 3 Intraclass correlation coefficients

From: Quantitative trait variation in ASD probands and toddler sibling outcomes at 24 months

 

All sibling pairs

Concordant pairs

Discordant pairs

n

ICC

p

n

ICC

p

n

ICC

p

ADI-R

 Social

355

0.03

0.096

81

− 0.20

0.595

274

0.02

0.112

 RRB

355

0.03

0.056

81

0.02

0.386

274

0.04

0.027

 Nonverbal communication

66

0.12

0.041

29

0.28

0.038

37

0.07

0.043

 Verbal communication

118

0.04

0.087

18

0.08

0.209

100

0.01

0.389

VABS-II

 ABC

306

0.13

< 0.001+

65

0.27

0.005

241

0.09

0.008

 Socialization

314

0.08

0.005

69

0.25

0.002+

245

0.03

0.207

 Communication

313

0.22

< 0.001+

69

0.41

0.002+

244

0.14

0.006

 Expressive

321

0.15

< 0.001+

71

0.35

0.001+

250

0.07

0.052

 Receptive

322

0.23

< 0.001+

71

0.50

< 0.001+

251

0.12

0.008

 Motor

281

0.11

0.027

62

0.05

0.344

219

0.11

0.053

 Fine

282

0.09

0.094

61

0.00

0.506

221

0.09

0.125

 Gross

281

0.21

< 0.001+

62

0.25

0.053

219

0.18

0.001+

  1. +significant at p ≤ 0.004 after Bonferroni correction (12 comparisons per group)