Fig. 4

FXS subject z-score deviations from healthy control. A FXS subjects’ z-scores of single flash b-wave amplitude vs flicker amplitude ERG measures and z-scores of LEA SYMBOLS® low-contrast contrast sensitivity test measured at 3 m and 5% nominal contrast vs 5 m at 10% nominal contrast. Electrophysiological and functional visual system measures are consistent in FXS subjects. B Histogram of FXS subjects’ (green) and control subjects’ (black) z-scores for all single-flash b-wave amplitude and flicker amplitude ERG measures and LEA SYMBOLS® low-contrast contrast sensitivity test measured at 3 m and 5% nominal contrast vs 5 m at 10% nominal contrast. FXS subject scores are deviated overall to the left