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Fig. 5 | Journal of Neurodevelopmental Disorders

Fig. 5

From: Increased 2-arachidonoyl-sn-glycerol levels normalize cortical responses to sound and improve behaviors in Fmr1 KO mice

Fig. 5

JZL-184 treatment improves inter-trial phase coherence to auditory chirp in Fmr1 KO mice 1 day post-treatment. Graphs show group mean differences between JZL-184-treated Fmr1 KO (N = 8) mice 1 day post-treatment compared to Fmr1 KO mice prior to treatment (N = 22) in left/right frontal, medial, and temporal regions of the mouse cortex. Monte Carlo statistical method on cluster analysis revealed a significant increase (p < 0.025) in ITPC to chirp 1 day post-treatment in the gamma-band range in LF, RM, LT, and RT regions. Abbreviations: LF, left frontal; RF, right frontal; LM, left medial; RM, right medial; LT, left temporal; RT, right temporal

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Journal of Neurodevelopmental Disorders

ISSN: 1866-1955

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