Fig. 3

Cerebral regions of the cortico-striatal functional circuits that expressed any difference between NF1 and typically developing children. The right angular gyrus (AG) is significantly more connected with the somatomotor striatal seed “striatum 2” of Choi’s functional atlas in NF1 children than in typically developing children. Age, sex, and GCOR are used as covariables; voxel threshold p < 0.001 p-uncorrected and cluster threshold p < 0.05