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Fig. 7 | Journal of Neurodevelopmental Disorders

Fig. 7

From: Computational analysis of cortical neuronal excitotoxicity in a large animal model of neonatal brain injury

Fig. 7

Effect of PP2 pre-treatment versus combination of PP2 administration following Hx and modulation of Src kinase activation of NMDARs (Ka). a Cartoon schematic showing the effect of Src on NMDAR activation in relation to pharmacological treatment timeline. b Comparison of PP2-pre-treatment (dotted line) versus Ka = 0.01 (light tone blue), Ka = 0.012 (mid-tone blue), Ka = 0.014 (blue) on cytoplasmic Ca2+ influx and c Bax expression

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