Table 1 Subject demographics and prevalence of core clinical features of SLC6A1-related disorder between the caregiver-reported (Searchlight) data and the provider-reported (Literature) data
From: Consistency of parent-report SLC6A1 data in Simons Searchlight with Provider-Based Publications
|  |  | Searchlight (n = 43) | Literature (total, n = 116) (gender, n = 58) (age, n = 40) | p value |
|---|---|---|---|---|
Demographics | Gender (M to F) | 22:21 | 26:32 | Â |
Age, mean (SD), range | 97Â months, 71, 7 to 280Â months | 125, 74, 16 to 336Â months | Â | |
Clinical characteristics |  | n = 35 | n = 116 |  |
Developmental delay or intellectual disability | 29/35 (82.9) | 51/55 (92.7) | 0.15 | |
Epilepsy | 28/35 (80) | 92/101 (91.1) | 0.08 | |
Autism spectrum disorder (ASD) | 11/35 (31.4) | 21/92 (22.8) | 0.36 | |
Attention deficit hyperactivity disorder (ADHD) | 4/35 (11.4) | 9/47 (19.2) | 0.38 | |
Hypotonia | 24/35 (68.6) | 8/46 (17.4) |  < 0.0001 | |
Movement disorder | 17/35 (48.6) | 13/46 (28.3) | 0.07 |