Table 1 Auditory brainstem responses in rodent models of ASD. Model names are written in bold if the result represents more than one study, or the majority of studies in the case where results from a single model are mixed. Numbers in subscript brackets refer to the relevant papers from the literature search, as numbered in Supplementary Table 1. Models are listed in alphabetical order
From: Auditory processing in rodent models of autism: a systematic review
Measure | Models increased compared to WT | Models unchanged compared to WT | Models decreased compared to WT |
|---|---|---|---|
ABR threshold | Adnp(28), Fmr1(67) | Chrna7(18), Cntnap2(70), Drd2(42), Mecp2(35, 86), Wnt1(52) | Wnt1(52) |
Peak IÂ Amplitude | Â | Cntnap2(70, 71), Drd2(42) | Â |
Peak IIÂ Amplitude | Cntnap2(70) | Drd2(42), Fmr1(67) | Â |
Peak IIIÂ Amplitude | Cntnap2(70), Fmr1(67) | Cntnap2(70,71), Drd2(42) | Â |
Peak IVÂ Amplitude | Cntnap2(70) | Cntnap2(70,71) | Â |
Peak IÂ Latency | Â | Cntnap2(70,71), Drd2(42) | Â |
Peak IIÂ Latency | Â | Drd2(42), Fmr1(67) | Â |
Peak IIIÂ Latency | Cntnap2(70) | Drd2(42), Mecp2(86) | Â |
Peak IVÂ Latency | Â | Cntnap2(71) | Cntnap2(70) |