Table 1 Clinical manifestations of leukomalacia in the preterm group and the term group

Basic information

 GA (weeks)

30.6 (28.8, 33.3)

38.7 (38.3, 39.4)

 < 0.001***

 BW (g)

1613.7 ± 558.2

3187.6 ± 592.9

 < 0.001***

 Male

76 (66.7%)

68 (65.4%)

0.824

 SGA

18 (15.8%)

12 (11.5%)

0.363

 5-min Apgar ≤ 7

42 (36.8%)

22 (21.2%)

0.011*

 Cesarean section

72 (63.2%)

56 (53.8%)

0.163

 Mechanical ventilation

70 (61.4%)

30 (28.8%)

 < 0.001***

Neonatal complications

 Apnea

40 (35.1%)

8 (7.7%)

 < 0.001***

 Neonatal seizures

5 (4.4%)

27 (26.0%)

 < 0.001***

 Symptomatic Hypoglycemia

5 (4.4%)

28 (26.9%)

 < 0.001***

 Sepsis

57 (50.0%)

18 (17.3%)

 < 0.001***

 hs-PDA

10 (8.8%)

2 (1.9%)

0.027*

 III-IV IVH

14 (12.3%)

6 (5.8%)

0.096

 Cerebral parenchymal Hemorrhage

19 (16.7%)

20 (19.2%)

0.622

 Purulent meningitis

12 (10.5%)

7 (6.8%)

0.332