Table 5 Caregiver impression of change

Unchanged

51.6%

(662/1282)

32.5%

(53/163)

38.1%

(56/147)

43.3%

(61/141)

Improved

27.2%

(349/1282)

47.2%

(77/163)

48.0%

(72/147)

44.0%

(62/141)

Reason for improvement: communication

36.7%

(128/349)

29.9%

(23/77)

29.2%

(21/72)

17.7%

(11/62)

First caregiver concern: communication

29.5%

(103/349)

41.6%

(32/77)

33.3%

(24/72)

27.4%

(17/62)

First caregiver concern: seizures

7.7%

(27/349)

10.4%

(8/77)

47.2%

(34/72)

17.7%

(11/62)

Worse

21.1%

(271/1282)

20.2%

(33/163)

12.9%

(19/147)

12.8%

(18/141)

Reason for worsening: seizures

19.2%

(52/271)

42.4%

(14/33)

63.2%

(12/19)

22.2%

(4/18)

First caregiver concern: seizures

21.4%

(58/271)

54.5%

(18/33)

78.9%

(15/19)

38.9%

(7/18)

First caregiver concern: communication

18.1%

(49/271)

3.0%

(1/33)

5.3%

(1/19)

5.6%

(1/18)