Fig. 1
From: A mouse model of ATRX deficiency with cognitive deficits and autistic traits
Validation of Atrx deletion in AtrxNEXCre male mice. A ATRX immunofluorescence staining of E13.5 control and AtrxNEXCre brain coronal cryosections is shown in red. DAPI counterstaining is shown in blue. Scale bar, 570 μm. B Magnified view of ATRX (top, red) and βIII-tubulin (bottom, green) staining in the developing cortical plate. Scale bar, 144 μm. C ATRX (red) and DAPI (blue) staining in the cortex and hippocampus of AtrxNEXCre and control mice at P20. D ATRX (red) and NeuN (green) staining in the cortex and hippocampus at P20. Cortex scale bar,100 μm and hippocampus scale bar, 400 μm. CA: cornu Ammonis, CP: cortical plate, Ctx: cortex, DG: dentate gyrus, GE: ganglionic eminence, LV: lateral ventricle, VZ: ventricular zone