Table 4 Adaptations made to the measurements
| Â | Adaptations made(% of all participants that started measurement) |
|---|---|
General adaptations (eye-tracking and fNIRS test environment) | - Participants were encouraged to sit in their own (wheel)chair (to increase comfort and decrease motion) - Some participants were strapped into their chair belts by the parent (to decrease motion) - Some younger participants sat in their parents’ lap - Several parents held their child’s hands when performing the measurements (to prevent the child from pulling off the equipment) |
Eye-tracking:  - VOF  - Social preference | - In case of failed calibration at first attempt, the task was started using a pre-set calibration, and the data were calibrated after the measurement using a post-calibration method (71%) - No adaptations made |
fNIRS | - Measurement started without fully optimizing light counts (removal of hair underneath the optodes), because the participant showed signs of protest (35%) - Reversal of filming direction for co-registration (start at CZ and end in front of the face, as starting filming in front of the face led the participants to watch along the direction of the camera) |
Indirect calorimetry | - Parents/caregivers held their child or their child’s hands (54%) - Distraction: videos and pictures were shown on the Ipad (42%) - A toy to hold in their hands (13%) - The measurement was done first on the parent to show the child how it works (4%) - The child was measured sleeping in his own stroller (4%) |
BIA | - Distraction was provided to the child in the form of a video or by making funny faces - Pillows were put underneath arms and between legs to prevent touching (13%) - The clips were hidden underneath a bandage (4%) - Parents held their child with non-conducting material in between them (4%) |
BOD POD | - The BOD POD has a scale on which participants have to stand still and balanced. Most children with AS could not do this. Therefore, their weight was assessed using a wheelchair scale, and manually inserted (61%) - Participant did not tolerate swimming cap, thus measurement was conducted without swimming cap (57%) - Calibrating Ipad or stuffed animal into the BOD POD (for distraction; 22%) |