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Fig. 2 | Journal of Neurodevelopmental Disorders

Fig. 2

From: Characterization of early markers of disease in the mouse model of mucopolysaccharidosis IIIB

Fig. 2

MPS IIIB mice exhibit subtle yet persistent alterations in gait. A Schematic of gait data collection timeline. B Number of data collection attempts needed across developmental timepoints. C-D Weight (C) and body length (D) across developmental gait collection ages. E Duration of braking for forelimbs during developmental gait assessment. F Hindpaw angle across developmental gait assessment timepoints. G-H Adult body length and weight for both females and males. I Number of data collection attempts needed for adult mice at 30 cm/s and 40 cm/s belt speeds. J Duration of braking for forelimbs at 30 cm/s belt speed for adult mice. K Percent stride in hindlimb shared stance at 40 cm/s belt speed for adult mice. L Percent of stride in swing (left panel) and stance (right panel) for hindlimbs at 40 cm/s belt speed for adult mice. Observed p values reported in figures. B-D, G, and H Grouped data presented as means ± SEM with individual data points presented as open circles. E, F, and I-L Covariate-adjusted means ± SEM accounting for changes in body length presented

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