Table 1 Demographics and Baseline Characteristics of Participants in C601/C602 and PATH for PWS
C601/C602 (N = 114) | PATH for PWS (N = 229) | |
|---|---|---|
Age, years mean ± SD | 13.1 ± 6.17 | 17.9 ± 9.49 |
Race, n (%) | ||
White | 98 (86.0%) | 185 (80.8%) |
Black or African American | 6 (5.3%) | 6 (2.6%) |
Asian | 1 (0.9%) | 4 (1.7%) |
American Indian or Alaska Native | 0 (0.0%) | 0 (0.0%) |
Native Hawaiian or Other Pacific Islander | 0 (0.0%) | 0 (0.0%) |
Other | 2 (1.8%) | 9 (3.9%) |
Multiple | 7 (6.1%) | 22 (9.6%) |
Not Reported | 0 (0.0%) | 3 (1.3%) |
Sex, n (%) | ||
Male | 48 (42.1%) | 110 (48.0%) |
Female | 66 (57.9%) | 119 (52.0%) |
PWS genetic subtype n (%) | ||
Deletion | 71 (62.3%) | 113 (49.3%) |
Non-deletion | 43 (37.7%) | 82 (35.8%) |
Not reported | 0 (0.0%) | 34 (14.8%) |
Weight, kg mean ± SD | 60.3 ± 29.69 | 66.7 ± 26.72 |
BMI, mean ± SD | 26.8 ± 9.3 | 28.9 ± 9.76 |
Baseline HQ-CT, mean ± SD | 21.3 ± 6.73 | 18.2 ± 4.99 |
Growth hormone use n (%) | ||
Yes (at both visits) | 95 (83.3%) | 130 (56.8%) |
No (at both visits) | 19 (16.7%) | 87 (38%) |
Only at baseline | 0 (0.0%) | 6 (2.6%) |
Only at 6 months | 0 (0.0%) | 6 (2.6%) |
PWSP Domain | N = 103 | N = 167 |
Aggressive Behaviors mean ± SD | 7.5 ± 3.81 | 8.9 ± 4.18 |
Anxiety mean ± SD | 12.9 ± 5.29 | 13.7 ± 5.05 |
Compulsivity mean ± SD | 12.0 ± 4.85 | 12.3 ± 4.48 |
Depression mean ± SD | 3.6 ± 2.27 | 3.8 ± 2.25 |
Disorder Thinking mean ± SD | 4.3 ± 3.33 | 4.5 ± 3.05 |
Rigidity/Irritability mean ± SD | 10.9 ± 5.33 | 12.0 ± 5.25 |