Fig. 2

Dlx1 mutant mice exhibited elevated locomotor responses to spatial novelty. (a) Both wild-type and Dlx1^−/− mice showed normal habituation to the novel environment, but the mutants’ activity was consistently elevated, as shown by the mean (± SEM) of activity count during the first 3 h in the locomotor activity level assay. (b) Locomotion of Dlx1 mutant mice was significantly elevated, especially in the first 3 h of activity, as shown by the mean (± SEM) of distance that the mice traveled. Dlx1^+/+, n = 8; Dlx1^−/−, n = 7. * = p < 0.05